Job Description

Join to apply for the Principal Scientist role at BeOne Medicines Join to apply for the Principal Scientist role at BeOne Medicines BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. General Description We are seeking a Clinical Biomarker Scientist to lead biomarker strategy and execution in clinical studies. The role involves designing and analyzing biomarker studies, collaborating with cross-functional teams, and managing external CROs to ensure high-quality data delivery. The ideal candidate will have a strong background in translational research, a deep understanding of clinical biomarkers, and excellent communication skills to drive insights that support clinical decision making and advance drug development. Essential Functions Of The Job Serve as the primary biomarker scientist for the clinical study team, ensuring biomarker strategies are integrated into clinical development plans. Deliver robust biomarker strategies at the study level, including target engagement, pharmacodynamics endpoints, patient selection and companion diagnostic development (if appropriate). Align biomarker strategies with clinical operational plans and functional area capabilities to ensure seamless execution. Author and edit biomarker sections of clinical protocols, ensuring scientific accuracy and clarity. Oversee the implementation of biomarker plans, including sample collection, alignment with consent forms, Human Biological Sample Management, and adherence to protocol and data standards. Collaborate with and manage external vendors and collaborators involved in clinical studies or translational research, including vendor evaluation and selection for biomarker activities. Evaluate and integrate emerging technologies into clinical studies, working closely with statisticians, bioinformatics teams, clinical and translational groups to address biomarker needs. Lead the analysis and summarization of study specific biomarker data, presenting findings and strategic recommendations to internal and external stakeholders. Stay informed on emerging scientific and technological advancement, contributing to the group’s continuous improvement and innovation. Qualifications 3+ years of experience with PhD in Life Science (e.g., Immunology, Molecular & Cellular Biology, Biochemistry, or related fields), with a strong emphasis on immunology research and its application to translational science. Demonstrated experience in clinical biomarkers and translational research in a pharmaceutical or biotech industry, particularly in Immunology, Oncology, or hematology. Deep understanding of immunological mechanisms, immune-related biomarkers, and their role in clinical drug development. Familiarity with the operational aspects of implementing biomarker strategies in clinical development is highly desirable. Proven ability to collaborate within cross-functional, international teams and thrive in a fast-paced dynamic environment. Global Competencies When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world. Fosters Teamwork Provides and Solicits Honest and Actionable Feedback Self-Awareness Acts Inclusively Demonstrates Initiative Entrepreneurial Mindset Continuous Learning Embraces Change Results-Oriented Analytical Thinking/Data Analysis Financial Excellence Communicates with Clarity Salary Range: $135,800.00 - $180,800.00 annually BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness. We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact accommodationsus@beonemed.com. 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